Hyavane
Sodium Hyaluronate Eye Drops
Formulation
Each mL contains: Sodium Hyaluronate 1mg
Pharmaceutical Dosage Form
Ophthalmic solution
Pharmacodynamic
- Because Sodium Hyaluronate (Hyavane) principle has the same structure as natural sodium hyaluronate and molecular weight of more than 4000KDa, it contains excellent biocompatibility and viscoelasticity.
- Because Sodium Hyaluronate (Hyavane) is produced through highly developed, unique microbial fermentation process, it contains low amount of proteins and nucleic acids and is completely devoid of inflammatory substances.
- Because Sodium Hyaluronate (Hyavane) contains high viscoelasticity, it shows good actions in maintaining cornea and protecting corneal endothelial cells.
- Sodium hyaluronate is a biological substance that has been shown in preclinical studies to accelerate the wound healing of corneal epithelium and to have water-holding properties. Its clinical usefulness has been established for the treatment of keratoconjunctival epithelial injury associated with dry eye syndrome or other disorders.
Pharmacokinetic
Sodium hyaluronate are widely distributed in human tissues and intracellular fluid, including cataract fluid.
Indications
Keratoconjunctival epithelial disorder resulting from the following diseases:
Endogenous diseases, eg Sjogren’s syndrome, Stevens-Johnson syndrome and sicca (dry eye)
Exogenous diseases caused by surgery, drugs, trauma and contact lens wearing, etc.
Dosage & Administration
For ophthalmic use only.
Usually, instill 1 drop at a time to the eye 5-6 times daily.
The dosage may be adjusted according to the patient’s symptoms.
Contraindications
Patients known to be hypersensitive to any of the composition.
Precaution
At the time of administration, instruct the patient to be careful not to touch the tip of the bottle to the eye directly in order to avoid the contamination of the eye drops. This product must not be used while wearing soft contact lenses.
Drug Interaction
No report of drug interaction.
Pregnancy And Lactation
There are no adequate studies of using this drug in pregnant women and lactation mother. This drug should be used during pregnant women and lactation mother only if the potential benefit justifies the potential risk.
Effects On Ability To Drive And Operate Machines
The drug does not affect ability to drive and operate machines.
Adverse Effects
Hypersensitivity: Blepharitis, eyelid dermatitis.
Ophthalmic: Itching, eye irritation, corneal lesion, eg. keratitis superficial diffuse.
Inform your doctor in case of any adverse reactions related to drug use.
For suspected adverse drug reaction report to FDA: www.fda.gov.ph
Overdosage
No report so far.
Storage
Store at temperatures not exceeding 30°C.
Use Term
3 years from manufacturing date.
Use drug within 1 month from date of opening.
Do not use if the drug is out of date
Availability
LDPE Plastic Bottle x 6mL (Box of 1’s)
FDA Registration No.
DRP-7680-04
